Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.37 |
| ▸ | TRPC4 | Q9UBN4 | 1/20 | 0.37 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACP1 | P24666 | 1/20 | 0.35 |
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1441268 | 0.95 | KCNH3 (0.41) | NPSR1ALDH1A1KCNH3LMNAMAPT | |
| SCHEMBL852975 | 0.82 | POLB (0.40) | ALDH1A1KDM4EHTTTSHRKCNH3 | |
| SCHEMBL4638849 | 0.82 | LMNA (0.34) | ALDH1A1KDM4EHTTLMNAMAPT | |
| Bromide SCHEMBL4638146 | 0.81 | LMNA (0.33) | ALDH1A1KDM4EHTTLMNAMAPT | |
| SCHEMBL3217738 | 0.81 | MAPT (0.42) | ALDH1A1KDM4EHTTTSHRKCNH3 | |
| SCHEMBL6177680 | 0.79 | KCNH3 (0.42) | ALDH1A1KDM4EHTTTSHRKCNH3 | |
| SCHEMBL6951347 | 0.78 | CA12 (0.38) | L3MBTL1ALDH1A1KDM4EHTTTSHR | |
| SCHEMBL6860751 | 0.77 | SLC2A1 (0.47) | ALDH1A1KDM4EHTTLMNAMAPK1 | |
| SCHEMBL11868462 | 0.76 | F2R (0.35) | NPSR1L3MBTL1ALDH1A1KDM4EAPAF1 | |
| SCHEMBL6963178 | 0.75 | KMT2A (0.34) | L3MBTL1ALDH1A1KDM4EHTTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7368566-B2 | Process and intermediates for preparing benzazepines | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-06 | — | — | US | disclosed |