Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.58 |
| ▸ | ITK | Q08881 | 1/20 | 0.58 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 3/20 | 0.54 |
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | MMP8 | P22894 | 3/20 | 0.54 |
| ▸ | MMP13 | P45452 | 3/20 | 0.54 |
| ▸ | NAMPT | P43490 | 1/20 | 0.54 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14182739 | 0.93 | MAOA (0.59) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182880 | 0.92 | PTPN1 (0.60) | MAOAMAOBPTPN1ITKBCAT2 | |
| SCHEMBL14182733 | 0.90 | RAB9A (0.60) | MAOAMAOBNPC1RAB9AITK | |
| SCHEMBL14182751 | 0.90 | KCNK3 (0.59) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182750 | 0.90 | RAB9A (0.60) | MAOAMAOBNPC1RAB9AITK | |
| SCHEMBL14182769 | 0.90 | KCNQ2 (0.64) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182882 | 0.88 | NPC1 (0.58) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182732 | 0.87 | KCNK3 (0.61) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182743 | 0.87 | KCNK3 (0.61) | MAOAMAOBNPC1RAB9AMAPT | |
| SCHEMBL14182710 | 0.87 | KCNK3 (0.61) | MAOAMAOBNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375118-B2 | Phenyl-indole compounds for modulating IgE and Inhibiting cellular proliferation | AVANIR PHARMACEUTICALS (US) | 2008-05-20 | — | — | US | disclosed |