Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185041 | 0.87 | SRD5A2 (0.37) | SRD5A2SRD5A1AR | |
| SCHEMBL14214531 | 0.87 | SRD5A2 (0.37) | SRD5A2SRD5A1AR | |
| SCHEMBL13611185 | 0.83 | SRD5A2 (0.49) | SRD5A2SRD5A1AR | |
| SCHEMBL13603625 | 0.83 | SRD5A2 (0.49) | SRD5A2SRD5A1AR | |
| SCHEMBL14214528 | 0.83 | SRD5A2 (0.37) | SRD5A2SRD5A1AR | |
| SCHEMBL27970660 | 0.81 | SRD5A2 (0.60) | SRD5A2SRD5A1AR | |
| SCHEMBL14185040 | 0.79 | ALDH1A1 (0.41) | SRD5A2SRD5A1AR | |
| SCHEMBL14214530 | 0.79 | ALDH1A1 (0.41) | SRD5A2SRD5A1AR | |
| SCHEMBL13603644 | 0.78 | SRD5A2 (0.50) | SRD5A2SRD5A1AR | |
| SCHEMBL13611190 | 0.78 | SRD5A2 (0.50) | SRD5A2SRD5A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | MERCK SHARP & DOHME CORP. | 2008-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080125399-A1 | 17 Beta-Acetamide-4-Azasteroids As Androgen Receptor Modulators | AR, CYP17A1, SHBG | SRD5A2 20/4885SRD5A1 18/4885AR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.