Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6747960 | 1.00 | SLC6A5 (0.44) | SLC6A5PAK1GBA1TSHRRAB9A | |
| SCHEMBL6751763 | 0.88 | TP53 (0.42) | SLC6A5PAK1TSHRMEN1KMT2A | |
| SCHEMBL14185050 | 0.86 | SLC6A5 (0.58) | SLC6A5PAK1TSHRRAB9AALDH1A1 | |
| SCHEMBL6747965 | 0.83 | PAK1 (0.62) | PAK1TSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL10925300 | 0.80 | PAK1 (0.61) | SLC6A5PAK1RAB9AALDH1A1NPC1 | |
| SCHEMBL10927535 | 0.80 | PAK1 (0.61) | SLC6A5PAK1RAB9AALDH1A1NPC1 | |
| SCHEMBL1725582 | 0.79 | PAK1 (0.62) | SLC6A5PAK1RAB9AALDH1A1NPC1 | |
| SCHEMBL13401493 | 0.78 | SLC6A5 (0.47) | SLC6A5TSHRRAB9AALDH1A1NPC1 | |
| SCHEMBL9999637 | 0.77 | PAK1 (0.46) | SLC6A5PAK1TSHRRAB9ANPC1 | |
| SCHEMBL2118555 | 0.74 | PAK1 (0.48) | PAK1TSHRRAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20070259889-A1 | Protein Binding Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2007-11-08 | — | — | US | disclosed |
| US-20070259889-A1 | Protein Binding Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259889-A1 | Protein Binding Compounds | FABP1, FABP3, FABP2 | SLC6A5 4421/4885PAK1 1205/4885GBA1 3293/4885 |
| US-20080103110-A1 | Compounds | ATIC, CDA, PAICS | SLC6A5 3513/4885PAK1 2906/4885GBA1 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.