Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.33 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | HINT1 | P49773 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14185071 | 0.91 | PRKACA (0.33) | PRKACAP2RY2P2RY4 | |
| SCHEMBL14185070 | 0.91 | PRKACA (0.33) | PRKACAP2RY2P2RY4 | |
| SCHEMBL14185074 | 0.91 | PRKACA (0.33) | PRKACAP2RY2P2RY4 | |
| SCHEMBL14185072 | 0.88 | SLC2A1 (0.33) | PRKACAP2RY2ABCG2ABCB1 | |
| SCHEMBL14185069 | 0.88 | SLC2A1 (0.33) | PRKACAP2RY2ABCG2ABCB1 | |
| SCHEMBL14185068 | 0.88 | SLC2A1 (0.33) | PRKACAP2RY2ABCG2ABCB1 | |
| SCHEMBL14185073 | 0.82 | POLA1 (0.33) | TDP1GBA1NLRP3ABCG2ABCB1 | |
| SCHEMBL14199831 | 0.82 | ADK (0.39) | P2RY2P2RY4P2RY14 | |
| SCHEMBL14178409 | 0.82 | ADK (0.39) | P2RY2P2RY4P2RY14 | |
| SCHEMBL14185076 | 0.73 | LPAR1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
| US-20080103110-A1 | Compounds | DRUG DISCOVERY LABORATORY AS (NO) | 2008-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080103110-A1 | Compounds | ATIC, CDA, PAICS | TDP1 1157/4885PRKACA 1656/4885GBA1 1444/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.