Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 6/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3132248 | 1.00 | TRHR (0.68) | TRHR | |
| SCHEMBL14185750 | 0.91 | TRHR (0.57) | TRHR | |
| SCHEMBL14185774 | 0.90 | TRHR (0.55) | TRHR | |
| SCHEMBL31332262 | 0.90 | TRHR (0.66) | TRHR | |
| SCHEMBL14185746 | 0.88 | TRHR (0.55) | TRHR | |
| SCHEMBL14185751 | 0.88 | TRHR (0.57) | TRHR | |
| SCHEMBL11182741 | 0.88 | TRHR (0.66) | TRHR | |
| SCHEMBL11331704 | 0.88 | TRHR (0.66) | TRHR | |
| SCHEMBL1371608 | 0.88 | TRHR (0.66) | TRHR | |
| SCHEMBL11327973 | 0.88 | TRHR (0.66) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7378397-B2 | TRH-degrading ectoenzyme inhibitors | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2008-05-27 | — | — | US | disclosed |