Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | GBA1 | P04062 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14190024 | 0.98 | MGLL (0.41) | MGLLFAAHPTGS1PTGS2GBA1 | |
| SCHEMBL14190026 | 0.98 | MGLL (0.41) | MGLLFAAHPTGS1PTGS2GBA1 | |
| SCHEMBL14190027 | 0.95 | MAPT (0.37) | MGLLFAAHPTGS1PTGS2GBA1 | |
| SCHEMBL19228012 | 0.86 | MAPT (0.36) | MGLLFAAHMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL16689781 | 0.79 | CYP3A4 (0.41) | MAPTL3MBTL1ALDH1A1GAACYP3A4 | |
| SCHEMBL9879851 | 0.79 | MGLL (0.41) | MGLLFAAHPTGS1PTGS2MAPT | |
| SCHEMBL4219840 | 0.77 | MGLL (0.42) | MGLLFAAHPTGS1PTGS2MAPT | |
| SCHEMBL7035794 | 0.77 | MGLL (0.46) | MGLLFAAHPTGS1PTGS2ALDH1A1 | |
| SCHEMBL11879565 | 0.74 | ALDH1A1 (0.35) | MGLLFAAHPTGS1PTGS2GBA1 | |
| SCHEMBL11087524 | 0.74 | GBA1 (0.36) | MGLLFAAHPTGS1PTGS2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371462-B2 | 1,3,5,7-tetramethylcyclotetrasiloxane and triallyl isocyanurate, a hydrosilylation catalyst, a silane coupling agent and/or an epoxy group-containing compound, and a silanol condensation catalyst | KANEKA CORPORATION (JP) | 2008-05-13 | — | — | US | disclosed |
| US-7371462-B2 | 1,3,5,7-tetramethylcyclotetrasiloxane and triallyl isocyanurate, a hydrosilylation catalyst, a silane coupling agent and/or an epoxy group-containing compound, and a silanol condensation catalyst | KANEKA CORPORATION (JP) | 2008-05-13 | — | — | US | disclosed |