Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10828029 | 0.88 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL25509703 | 0.83 | TSHR (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL10127341 | 0.82 | LMNA (0.46) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL14946496 | 0.82 | CHRNB2 (0.42) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL22281741 | 0.82 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL15254984 | 0.81 | CHRNB2 (0.34) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL23847130 | 0.79 | LMNA (0.52) | LMNA | |
| SCHEMBL10127585 | 0.79 | LMNA (0.52) | LMNA | |
| SCHEMBL22861460 | 0.78 | CHRNB2 (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR | |
| SCHEMBL14946494 | 0.78 | KDM5A (0.36) | CHRNB2CHRNB4CHRNA3CHRNA4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1935986-A2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-06-25 | — | — | EP | disclosed |