Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.38 |
| ▸ | KLK1 | P06870 | 2/20 | 0.38 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.38 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192520 | 0.90 | THRB (0.58) | THRBMAPTSMN1; SMN2TP53NPC1 | |
| SCHEMBL14192345 | 0.86 | THRB (0.62) | THRBMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL9817392 | 0.86 | MAPT (0.67) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL14192453 | 0.82 | THRB (0.61) | THRBMAPTSMN1; SMN2RARBKMT2A | |
| SCHEMBL11307746 | 0.81 | MAPT (0.67) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL9817329 | 0.81 | MAPT (0.67) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL9817770 | 0.81 | MAPT (0.67) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL14192452 | 0.81 | THRB (0.68) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL14192518 | 0.81 | THRB (0.68) | THRBMAPTSMN1; SMN2TP53RARB | |
| SCHEMBL14192528 | 0.80 | MAPT (0.64) | THRBMAPTSMN1; SMN2TP53NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |