Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192527 | 0.80 | THRB (0.56) | MAPTTHRBTP53SMN1; SMN2RAB9A | |
| SCHEMBL14192520 | 0.80 | THRB (0.58) | MAPTTHRBTP53SMN1; SMN2RAB9A | |
| SCHEMBL9722206 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL9722476 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL9722346 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL9722429 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL9722186 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL9722412 | 0.79 | MAPT (0.58) | MAPTTHRBTP53SMN1; SMN2NPC1 | |
| SCHEMBL14192453 | 0.77 | THRB (0.61) | MAPTTHRBSMN1; SMN2KMT2A | |
| SCHEMBL14192345 | 0.76 | THRB (0.62) | MAPTTHRBSMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |