Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | JAK1 | P23458 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16563109 | 0.83 | ALDH5A1 (0.52) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL14192544 | 0.78 | KDM4E (0.57) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL4420270 | 0.75 | MAOB (0.52) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL25284739 | 0.75 | AURKA (0.50) | MEN1ALDH1A1KMT2AHSD17B10AURKA | |
| SCHEMBL28186415 | 0.72 | EPHX2 (0.50) | MAPTKMT2AAURKATPX2TEK | |
| SCHEMBL22390560 | 0.72 | ESR1 (0.52) | SMN1; SMN2AURKATPX2 | |
| SCHEMBL505538 | 0.72 | AURKA (0.69) | ALDH1A1HSD17B10AURKATPX2MMP2 | |
| SCHEMBL28243402 | 0.71 | SCN5A (0.47) | AURKATPX2 | |
| SCHEMBL22561053 | 0.71 | MEN1 (0.45) | KDM4EMEN1ALDH1A1EGFRTP53 | |
| SCHEMBL22815931 | 0.71 | AURKA (0.54) | AURKATPX2HDAC6MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |