Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.57 |
| ▸ | JAK1 | P23458 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2126134 | 0.82 | CES2 (0.59) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL14192530 | 0.78 | KDM4E (0.53) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL30827199 | 0.73 | KDM4E (1.00) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL149980 | 0.73 | KDM4E (1.00) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29707545 | 0.73 | KDM4E (1.00) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL14192539 | 0.72 | THRB (0.70) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL4315033 | 0.72 | ALDH5A1 (0.70) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL8871990 | 0.72 | ALDH5A1 (0.53) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL3557840 | 0.72 | KDM4E (0.89) | KDM4EHSD17B10MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL2247505 | 0.71 | KDM4E (0.72) | KDM4EHSD17B10EGFRTP53CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |