Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 10/20 | 0.41 |
| ▸ | THRA | P10827 | 7/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192399 | 1.00 | ELANE (0.44) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192324 | 0.96 | ELANE (0.47) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192385 | 0.93 | ELANE (0.44) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192424 | 0.92 | THRB (0.44) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192321 | 0.88 | THRB (0.47) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192564 | 0.86 | F2 (0.43) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL14192403 | 0.85 | THRB (0.44) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL3617483 | 0.85 | THRB (0.51) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL3617484 | 0.85 | THRB (0.51) | ELANEKMT2AHTTSMN1; SMN2TDP1 | |
| SCHEMBL13135346 | 0.83 | HTT (0.58) | ELANEKMT2AHTTSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |