Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192390 | 0.93 | THRB (0.44) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL14192540 | 0.86 | ELANE (0.44) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL14192399 | 0.86 | ELANE (0.44) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL14192432 | 0.86 | THRB (0.44) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL12154174 | 0.85 | THRB (0.44) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL11406359 | 0.85 | F2 (0.49) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL8211820 | 0.83 | F2 (0.54) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9302661 | 0.83 | F2 (0.54) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9302657 | 0.83 | F2 (0.54) | F2THRBKMT2AHTTSMN1; SMN2 | |
| SCHEMBL9486971 | 0.83 | F2 (0.54) | F2THRBKMT2AHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |