Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.51 |
| ▸ | THRA | P10827 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192568 | 0.97 | THRA (0.48) | RARBTHRATP53TSHRTHRB | |
| SCHEMBL14192516 | 0.87 | RARB (0.53) | RARBTHRATP53TSHRTHRB | |
| SCHEMBL14192583 | 0.85 | RARB (0.45) | RARBTHRATP53TSHRTHRB | |
| SCHEMBL9742462 | 0.85 | RARB (0.49) | RARBTHRA | |
| SCHEMBL9742895 | 0.85 | RARB (0.49) | RARBTHRA | |
| SCHEMBL9744005 | 0.85 | RARB (0.49) | RARBTHRA | |
| SCHEMBL9743257 | 0.83 | RARB (0.51) | RARBTHRATP53TSHRPLA2G4B | |
| SCHEMBL9744448 | 0.83 | RARB (0.51) | RARBTHRATP53TSHRPLA2G4B | |
| SCHEMBL9742892 | 0.83 | RARB (0.51) | RARBTHRATP53TSHRPLA2G4B | |
| SCHEMBL9743930 | 0.83 | RARB (0.51) | RARBTHRATP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |