Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 4/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 5/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192586 | 0.86 | PTPN11 (0.44) | RARBPTPN11THRATHRBMEN1 | |
| SCHEMBL14192567 | 0.85 | RARB (0.51) | RARBPTPN11TP53TSHRTHRA | |
| SCHEMBL14192568 | 0.82 | THRA (0.48) | RARBTP53TSHRTHRATHRB | |
| SCHEMBL14192593 | 0.81 | ALDH5A1 (0.41) | RARBTP53THRATHRBMEN1 | |
| SCHEMBL14219187 | 0.80 | ALDH5A1 (0.43) | RARBTP53THRATHRBMEN1 | |
| SCHEMBL6538549 | 0.77 | TP53 (0.64) | RARBTP53TSHRTHRATHRB | |
| SCHEMBL14192560 | 0.76 | THRB (0.54) | THRATHRBMEN1KMT2A | |
| SCHEMBL28657555 | 0.75 | TP53 (0.67) | RARBTP53TSHRTHRATHRB | |
| SCHEMBL14192516 | 0.74 | RARB (0.53) | RARBPTPN11TP53TSHRTHRA | |
| SCHEMBL14088620 | 0.74 | RARB (0.39) | RARBPTPN11THRATHRBPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |