Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.60 |
| ▸ | THRA | P10827 | 5/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | RARB | P10826 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | RARA | P10276 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192539 | 0.87 | THRB (0.70) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192353 | 0.86 | THRB (0.76) | THRBTHRAMEN1KMT2A | |
| SCHEMBL14192532 | 0.83 | THRB (0.59) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192473 | 0.82 | THRB (0.72) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192545 | 0.81 | THRB (0.61) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192556 | 0.81 | THRB (0.61) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192423 | 0.81 | THRB (0.68) | THRBTHRAMEN1KMT2AALDH1A1 | |
| SCHEMBL10462600 | 0.81 | THRB (0.91) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192407 | 0.81 | THRB (0.91) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192458 | 0.81 | THRB (0.73) | THRBTHRAMEN1KMT2ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |