Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 10/20 | 0.59 |
| ▸ | THRA | P10827 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | RARB | P10826 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192571 | 0.89 | THRB (0.50) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192438 | 0.86 | THRB (0.71) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192492 | 0.86 | KMT2A (0.51) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL4578912 | 0.85 | THRB (0.71) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192539 | 0.83 | THRB (0.70) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192573 | 0.83 | THRB (0.60) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL4578159 | 0.82 | THRB (0.76) | THRBTHRAMEN1KMT2AMAPT | |
| SCHEMBL14192452 | 0.82 | THRB (0.68) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL14192518 | 0.82 | THRB (0.68) | THRBTHRAMEN1KMT2ARARB | |
| SCHEMBL3618792 | 0.82 | THRB (0.76) | THRBTHRAMEN1KMT2ARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |