Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 7/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192541 | 0.87 | CYP2C9 (0.46) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192322 | 0.84 | CYP2C9 (0.56) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192428 | 0.83 | CYP2C9 (0.59) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14373521 | 0.83 | THRB (0.48) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192554 | 0.82 | CYP2C9 (0.41) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192581 | 0.81 | THRB (0.38) | MAPTMEN1KMT2ATHRBTHRA | |
| SCHEMBL14192416 | 0.81 | CYP2C9 (0.52) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192396 | 0.81 | CYP2C9 (0.52) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192450 | 0.81 | RAB9A (0.47) | CYP2C9MAPTALDH1A1LMNAMEN1 | |
| SCHEMBL14192552 | 0.80 | CYP2C9 (0.43) | CYP2C9MAPTALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |