Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.40 |
| ▸ | ABAT | P80404 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.40 |
| ▸ | THRB | P10828 | 7/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | THRA | P10827 | 6/20 | 0.37 |
| ▸ | ACACB | O00763 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14192466 | 0.96 | ALDH5A1 (0.43) | ALDH5A1ABATFFAR1THRBAKT1 | |
| SCHEMBL14192590 | 0.81 | MEN1 (0.51) | ALDH5A1ABATTHRBAKT1THRA | |
| SCHEMBL14192454 | 0.78 | ALDH5A1 (0.61) | ALDH5A1ABATFFAR1THRBAKT1 | |
| SCHEMBL16182691 | 0.76 | ACACB (0.45) | FFAR1THRBACACBCYP3A4RARB | |
| SCHEMBL14192559 | 0.76 | MEN1 (0.56) | ALDH5A1ABATTHRBAKT1THRA | |
| SCHEMBL14192600 | 0.75 | MAPT (0.41) | ALDH5A1ABATTHRBAKT1THRA | |
| SCHEMBL14219057 | 0.75 | ALDH5A1 (0.51) | ALDH5A1ABATFFAR1THRBAKT1 | |
| SCHEMBL14192426 | 0.73 | THRB (0.74) | THRBTHRAACACBMEN1KMT2A | |
| SCHEMBL14192418 | 0.73 | THRB (0.74) | THRBTHRAACACBMEN1KMT2A | |
| SCHEMBL4315033 | 0.73 | ALDH5A1 (0.70) | ALDH5A1ABATTHRBAKT1THRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |
| US-7357964-B2 | Liquid-crystalline vinyl ketone derivatives and their polymers | CHISSO CORPORATION (JP) | 2008-04-15 | — | — | US | disclosed |