Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13865925 | 0.87 | CHEK1 (0.34) | CTSA | |
| SCHEMBL13870873 | 0.74 | ERN1 (0.35) | — | |
| SCHEMBL13865929 | 0.72 | CHEK1 (0.36) | — | |
| SCHEMBL13865921 | 0.70 | CHEK1 (0.37) | CYP3A4TSHR | |
| SCHEMBL13865922 | 0.70 | FGFR1 (0.35) | — | |
| SCHEMBL13865927 | 0.69 | ALDH1A1 (0.41) | — | |
| SCHEMBL13866124 | 0.68 | ALDH1A1 (0.41) | — | |
| SCHEMBL8757254 | 0.62 | PDE10A (0.33) | CTSA | |
| SCHEMBL28296673 | 0.61 | PTPN1 (0.49) | — | |
| SCHEMBL6978184 | 0.61 | AOC3 (0.48) | CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7388010-B2 | Quinoxalinone derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-06-17 | — | — | US | disclosed |