Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31166945 | 0.88 | PTPN1 (0.42) | PTPN1KCNN4SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL29381303 | 0.82 | L3MBTL1 (0.42) | PTPN1KCNN4SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL20608004 | 0.82 | L3MBTL1 (0.42) | PTPN1KCNN4SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL17528451 | 0.82 | PTPN1 (0.36) | PTPN1KCNN4MRGPRX4 | |
| SCHEMBL18323724 | 0.81 | ALDH1A1 (0.47) | PTPN1L3MBTL1TDP1ALDH1A1GLA | |
| SCHEMBL19541455 | 0.80 | HTR1B (0.38) | HTR1BL3MBTL1TDP1SCN8AALDH1A1 | |
| SCHEMBL22182755 | 0.80 | HTR1B (0.55) | PTPN1HTR1BSMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL256772 | 0.80 | L3MBTL1 (0.47) | HTR1BL3MBTL1TDP1ALDH1A1GLA | |
| SCHEMBL2279174 | 0.79 | ALDH1A1 (0.50) | PTPN1SMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL30179627 | 0.79 | ALDH1A1 (0.50) | PTPN1SMN1; SMN2L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109843856-A | KRAS G12C inhibitor | 米拉蒂治疗股份有限公司 | 2019-06-04 | — | — | CN | disclosed |