Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 12/20 | 0.34 |
| ▸ | DRD3 | P35462 | 10/20 | 0.34 |
| ▸ | DRD2 | P14416 | 9/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14197360 | 0.78 | CSF1R (0.53) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL13976950 | 0.77 | GPR84 (0.45) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL14194977 | 0.77 | CYP3A4 (0.45) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL14196167 | 0.75 | CYP3A4 (0.54) | GPR84METDRD4DRD3CYP3A4 | |
| SCHEMBL14198431 | 0.71 | FGFR1 (0.39) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL14196946 | 0.71 | GPR84 (0.60) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL14194093 | 0.68 | CSF1R (0.56) | GPR84METDRD3CYP3A4HTR1A | |
| SCHEMBL14197867 | 0.67 | CSF1R (0.53) | GPR84METDRD3CYP3A4HTR1A | |
| SCHEMBL14198419 | 0.66 | CSF1R (0.61) | GPR84METDRD4DRD3DRD2 | |
| SCHEMBL14196175 | 0.66 | CSF1R (0.51) | GPR84METDRD4DRD3CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063888-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |