SCHEMBL14194336

SCHEMBL14194336

Cc1nc2cc(S[SH](=O)=O)ccc2s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 5/20 0.51
▸ NPC1 O15118 3/20 0.51
▸ RAB9A P51151 3/20 0.51
▸ HSD17B10 Q99714 2/20 0.47
▸ ALDH1A1 P00352 5/20 0.47
▸ TP53 P04637 2/20 0.47
▸ PKM P14618 2/20 0.47
▸ MAPT P10636 1/20 0.47
▸ HPGD P15428 1/20 0.47
▸ POLB P06746 2/20 0.46
▸ GAA P10253 1/20 0.44
▸ KMT2A Q03164 1/20 0.43
▸ LMNA P02545 2/20 0.41
▸ NPSR1 Q6W5P4 1/20 0.41
▸ HTT P42858 2/20 0.39
▸ CASP3 P42574 1/20 0.39
▸ SENP7 Q9BQF6 1/20 0.39
▸ TRPV1 Q8NER1 1/20 0.39
▸ TDP1 Q9NUW8 1/20 0.39
▸ ALOX15 P16050 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6140766 0.80 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL15083825 0.78 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL12210616 0.75 SMN1; SMN2 (0.53) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL13412866 0.75 SMN1; SMN2 (0.49) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL2089542 0.72 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL92781 0.71 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
Bromide SCHEMBL10996884 0.70 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL10254309 0.68 ALDH1A1 (0.57) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL991889 0.68 ALDH1A1 (0.57) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1
SCHEMBL1319670 0.68 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9AHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7364841-B2 Comprising support having thereon light-insensitive organic silver salt grains, photosensitive silver halide grains, a reducing agent for silver ions and a binder; improved storage stability, image lasting quality; use in medical diagnosis and graphic arts KONICA MINOLTA & MEDICAL GRAPHIC, INC. (JP) 2008-04-29 — — US disclosed
US-7335466-B2 Silver salt photothermographic dry imaging material, image recording method and image forming method for the same KONICA MINOLTA HOLDINGS, INC. (JP) 2008-02-26 — — US disclosed
US-7175978-B2 Silver salt photothermographic dry imaging material KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-02-13 — — US disclosed
US-20070003886-A1 SILVER SALT PHOTOTHERMOGRAPHIC DRY IMAGING MATERIAL KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2007-01-04 — — US disclosed
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