SCHEMBL1319670

SCHEMBL1319670

Cc1nc2cc(F)ccc2s1

nearest known ligand 0.57

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
HSD17B10 Q99714 2/20 0.57
PKM P14618 2/20 0.57
ALDH1A1 P00352 2/20 0.57
TP53 P04637 1/20 0.57
MAPT P10636 1/20 0.57
HPGD P15428 1/20 0.57
GAA P10253 1/20 0.53
POLB P06746 2/20 0.53
DYRK1A Q13627 1/20 0.53
KMT2A Q03164 1/20 0.50
ILK Q13418 1/20 0.50
AHR P35869 1/20 0.49
TRPV1 Q8NER1 1/20 0.47
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30421999 1.00 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL13862697 0.85 TRPV1 (0.52) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL2615304 0.84 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL31036744 0.84 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL2615303 0.84 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL11153027 0.81 ALDH1A1 (0.55) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL92781 0.79 SMN1; SMN2 (0.61) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL4920329 0.79 TRPV1 (0.65) SMN1; SMN2NPC1RAB9APKMTP53
Bromide SCHEMBL10996884 0.78 SMN1; SMN2 (0.59) SMN1; SMN2NPC1RAB9AHSD17B10PKM
SCHEMBL2432396 0.78 F2RL3 (0.51) SMN1; SMN2NPC1RAB9APKMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355041-A Method for underwater bonding 汉高股份有限及两合公司 2024-07-16 CN claimed
CN-113045993-A Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof 西南交通大学 2021-06-29 CN claimed
EP-3464446-B1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2021-06-23 EP claimed
CN-109476874-B Two-part cyanoacrylate curable adhesive systems 汉高知识产权控股有限责任公司 2021-04-16 CN claimed
US-10655015-B2 Tire crumb-based bitumen polymer for producing a lower viscosity asphalt with improved tolerance to high temperatures Argopro Group LLC (US) 2020-05-19 US claimed
US-20200095424-A1 TIRE CRUMB-BASED BITUMEN POLYMER FOR PRODUCING A LOWER VISCOSITY ASPHALT WITH IMPROVED TOLERANCE TO HIGH TEMPERATURES Argopro Group LLC 2020-03-26 US claimed
EP-3464446-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2019-04-10 EP claimed
US-10100235-B2 Two-part cyanoacrylate curable adhesive system Henkel IP & Holding GmbH (DE) 2018-10-16 US claimed
WO-2017202698-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM Henkel IP & Holding GmbH (DE) 2017-11-30 WO claimed
US-20170335151-A1 TWO-PART CYANOACRYLATE CURABLE ADHESIVE SYSTEM HENKEL AG & CO. KGAA (DE) 2017-11-23 US claimed
EP-2346956-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES Loctite (R & D) Limited (IE) 2011-07-27 EP claimed
WO-2010046412-A1 ACTIVATORS FOR TWO PART CYANOACRYLATE ADHESIVES LOCTITE (R & D) LIMITED (IE) 2010-04-29 WO claimed
EP-4732907-A1 STYRYL BENZOTHIAZOLIUM SALTS AND ITS USES AGAINST PARASITIC INFECTIONS Consejo Superior de Investigaciones Científicas (CSIC) (ES) 2026-04-29 EP disclosed
EP-4219460-B1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA INC (US) 2025-02-26 EP disclosed
CN-119522221-A Cyanine dye, preparation method and application thereof, sample analysis method and analyzer 深圳迈瑞生物医疗电子股份有限公司 2025-02-25 CN disclosed
US-20250011324-A1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA, INC., 2025-01-09 US disclosed
EP-0545380-A1 Silver halide emulsions spectrally sensitized to infrared radiation with novel cyanine dyes POLAROID CORPORATION (US) 1993-06-09 EP disclosed
EP-0533695-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY. PFIZER (US) 1993-03-31 EP disclosed
CN-1057839-A The azepine benzoglyoxaline that is used for the treatment of asthma, sacroiliitis and relative disease PFIZER (US) 1992-01-15 CN disclosed
WO-1991017163-A1 IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY PFIZER INC. (US) 1991-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250011324-A1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS TGM2, TGM3, TGM1 SMN1; SMN2 2176/4885NPC1 3220/4885RAB9A 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.