⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14196171 | 0.81 | CYP3A4 (0.35) | — | |
| SCHEMBL14197869 | 0.80 | CSF1R (0.43) | — | |
| SCHEMBL13977459 | 0.79 | — | — | |
| SCHEMBL14197870 | 0.70 | CSF1R (0.49) | — | |
| SCHEMBL14197362 | 0.69 | CYP2C19 (0.33) | — | |
| SCHEMBL14198421 | 0.69 | CSF1R (0.56) | — | |
| SCHEMBL14194091 | 0.69 | CYP3A4 (0.60) | — | |
| SCHEMBL14197360 | 0.69 | CSF1R (0.53) | — | |
| SCHEMBL14194082 | 0.68 | CYP3A4 (0.48) | — | |
| SCHEMBL14198428 | 0.68 | CYP3A4 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008064265-A2 | COMPOUNDS MODULATING C-FMS AND/OR C-KIT ACTIVITY AND USES THEREFOR | PLEXXIKON, INC. (US) | 2008-05-29 | — | — | WO | disclosed |