Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 12/20 | 0.40 |
| ▸ | CDK9 | P50750 | 12/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14997369 | 0.84 | CDK2 (0.43) | CDK2CDK9IDO1 | |
| SCHEMBL3285457 | 0.84 | CDK2 (0.43) | CDK2CDK9IDO1 | |
| SCHEMBL14103878 | 0.82 | CDK2 (0.43) | CDK2CDK9 | |
| SCHEMBL18231808 | 0.76 | CDK2 (0.36) | CDK2CDK9 | |
| SCHEMBL2746172 | 0.75 | ALDH1A1 (0.38) | CDK2CDK9 | |
| SCHEMBL14205741 | 0.73 | CDK2 (0.37) | CDK2CDK9 | |
| SCHEMBL2746452 | 0.73 | CYP11B1 (0.37) | CDK2CDK9 | |
| SCHEMBL9610888 | 0.71 | CDK2 (0.39) | CDK2CDK9 | |
| SCHEMBL2745762 | 0.71 | CDK2 (0.46) | CDK2CDK9 | |
| SCHEMBL121954 | 0.70 | ALDH1A1 (0.43) | CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108667-A1 | Multi-substituted pyridyl sulfoximines and their use as insecticides | PIR, PNPO, PRDX4 | CDK2 2547/4885CDK9 3431/4885IDO1 137/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.