Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 17/20 | 0.61 |
| ▸ | HTR2A | P28223 | 16/20 | 0.61 |
| ▸ | HTR1A | P08908 | 14/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.57 |
| ▸ | HTR2C | P28335 | 2/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.57 |
| ▸ | HRH1 | P35367 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.57 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.57 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.57 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL460865 | 0.79 | DRD2 (0.49) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL8338559 | 0.79 | DRD2 (0.49) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL9910963 | 0.78 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL5623016 | 0.78 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL6091966 | 0.78 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL12345546 | 0.78 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| Hydrochloric Acid SCHEMBL1443956 | 0.78 | DRD2 (0.48) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL7702842 | 0.77 | DRD2 (0.79) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL7291846 | 0.77 | DRD2 (0.66) | DRD2HTR2AHTR1AKCNH2HTR2C | |
| SCHEMBL7292040 | 0.77 | DRD2 (0.79) | DRD2HTR2AHTR1AKCNH2HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7355042-B2 | Treatment of CNS disorders using CNS target modulators | HYPNION, INC. (US) | 2008-04-08 | — | — | US | disclosed |