Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27508757 | 0.90 | LOXL2 (0.51) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL131711 | 0.84 | LOXL2 (0.70) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL28631592 | 0.82 | LOXL2 (0.68) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL63426 | 0.82 | LOXL2 (0.68) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL28800124 | 0.82 | LOXL2 (0.68) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL28291325 | 0.81 | CYP4A11 (0.62) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL27816868 | 0.81 | CA12 (0.48) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL28533242 | 0.80 | LOXL2 (0.66) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL28529337 | 0.80 | LOXL2 (0.66) | LOXL2CYP4A11CYP4F2CA1CA2 | |
| SCHEMBL69454 | 0.79 | LOXL2 (0.70) | LOXL2CYP4A11CYP4F2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020047487-A1 | METHODS FOR TREATING CANCER WITH RORGAMMA INHIBITORS AND STATINS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-03-05 | — | — | WO | disclosed |
| CN-1960967-B | Triketone-based compound, method for producing the same and herbicide containing the same | ISHIHARA SANGYO KAISHA | 2010-12-29 | — | — | CN | disclosed |
| EP-1483285-B1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2008-05-07 | — | — | EP | disclosed |
| CN-1332944-C | Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate | SHANGHAI INST ORGANIC CHEM (CN) | 2007-08-22 | — | — | CN | disclosed |
| CN-1960967-A | Triketone-based compound, method for producing the same and herbicide containing the same | ISHIHARA SANGYO KAISHA (JP) | 2007-05-09 | — | — | CN | disclosed |
| CN-1651408-A | Amino acid accelerated CuI catalyzed aryl halide and coupling reaction of alkyl sulfonate | SHANGHAI INST ORGANIC CHEM (CN) | 2005-08-10 | — | — | CN | disclosed |
| CN-1187349-C | 3-(4.5-dihydroisoxazole-5-yl)-benzoylpyrazole | BASF AG (DE) | 2005-02-02 | — | — | CN | disclosed |
| CN-1553891-A | Method for producing 3-bromomethylbenzoic acids | �Ϻ���ͨ��ѧ | 2004-12-08 | — | — | CN | disclosed |
| WO-2003076457-A1 | INHIBITORS OF THE BLOOD-CLOTTING FACTOR Xa, PRODUCTION THEREOF AND USE OF THE SAME | CURACYTE AG (DE) | 2003-09-18 | — | — | WO | disclosed |
| CN-1413209-A | 3-(4.5-dihydroisoxazole-5-yl)-benzoylpyrazole | BASF AG (DE) | 2003-04-23 | — | — | CN | disclosed |