SCHEMBL63426

SCHEMBL63426

COC(=O)c1ccc(CO)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 1/20 0.68
CYP4A11 Q02928 2/20 0.67
CYP4F2 P78329 1/20 0.65
HPGD P15428 2/20 0.61
SMN1; SMN2 Q16637 2/20 0.61
CA1 P00915 3/20 0.59
CA2 P00918 3/20 0.59
TDP1 Q9NUW8 1/20 0.59
CA12 O43570 1/20 0.59
CA7 P43166 1/20 0.59
CA9 Q16790 1/20 0.59
CA14 Q9ULX7 1/20 0.59
MAPT P10636 2/20 0.59
TSHR P16473 2/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
ALDH1A1 P00352 2/20 0.53
KDM4E B2RXH2 1/20 0.53
NPC1 O15118 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28631592 1.00 LOXL2 (0.68) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL28529337 0.98 LOXL2 (0.66) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL28533242 0.98 LOXL2 (0.66) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL5893077 0.94 LOXL2 (0.61) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL481297 0.94 LOXL2 (0.61) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL8168374 0.91 LOXL2 (0.58) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL4597965 0.91 CA1 (0.58) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL13266994 0.89 PTPN1 (0.59) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL25547718 0.89 SMN1; SMN2 (0.69) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2
SCHEMBL13245413 0.89 PTPN11 (0.56) LOXL2CYP4A11CYP4F2HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606625-A Moisture-heat-resistant polyurethane heat-conducting structural adhesive and preparation method thereof 广东德聚技术股份有限公司 2023-08-18 CN claimed
CN-113149861-B P-hydroxymethyl benzoic acid (alkyl ester) -4-azobenzene and preparation method and application thereof 郑州大学 2023-01-31 CN claimed
CN-101531593-B The synthetic method of 4 (methylol) methyl benzoates 大连九信精细化工有限公司 2017-12-05 CN claimed
JP-4537315-B2 2010-09-01 JP claimed
US-7666863-B2 Benzofuran compounds, compositions and methods for treatment and prophylaxis of hepatitis C viral infections and associated diseases VIROPHARMA INCORPORATED (US) 2010-02-23 US claimed
CN-101531593-A Synthesis method of 4- (hydroxymethyl) methyl benzoate DALIAN KAIFEI FINE CHEMICALS C 2009-09-16 CN claimed
EP-1349878-B1 METHOD FOR PRODUCING A CATALYST FOR HOMO- OR CO-POLYMERIZATION OF ETHYLENE SAMSUNG GENERAL CHEMICALS CO (KR) 2009-04-22 EP claimed
US-20070270598-A1 Process for one pot conversion of artemisinin into artelinic acid COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2007-11-22 US claimed
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES SAHA ASHIS K 2007-10-04 US claimed
WO-2007105048-A1 A PROCESS FOR ONE POT CONVERSION OF ARTEMISININ INTO ARTELINIC ACID COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2007-09-20 WO claimed
CN-1258681-A Catalyst for olefines polymerization and copolymerization SAMSUNG COMPREHENSIVE CHEMICAL (KR) 2000-07-05 CN claimed
WO-2000018721-A1 SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY MONSANTO COMPANY (US) 2000-04-06 WO claimed
EP-0813516-B1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEM CO (US) 1999-12-01 EP claimed
EP-0813516-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEMICAL COMPANY (US) 1997-12-29 EP claimed
EP-0809636-A1 SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1997-12-03 EP claimed
WO-1996027578-A1 PROCESS FOR THE PREPARATION OF STILBENEDICARBOXYLATE ESTERS EASTMAN CHEMICAL COMPANY (US) 1996-09-12 WO claimed
WO-1996025405-A1 SUBSTITUTED ISOXAZOLES FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1996-08-22 WO claimed
US-5473098-A Process for the preparation of stilbenedicarboxylate esters EASTMAN CHEMICAL COMPANY (US) 1995-12-05 US claimed
WO-1994003168-A1 5 S PENEM DERIVATIVES, THEIR PREPARATION AND USE SMITHKLINE BEECHAM PLC (GB) 1994-02-17 WO claimed
US-4220753-A Alkyl alkoxymethylbenzoates STANDARD OIL COMPANY (INDIANA) (US) 1980-09-02 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070231318-A1 BENZOFURAN COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT AND PROPHYLAXIS OF HEPATITIS C VIRAL INFECTIONS AND ASSOCIATED DISEASES BBOX1, HAVCR2, CYP2E1 LOXL2 1377/4885CYP4A11 322/4885CYP4F2 95/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.