Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.61 |
| ▸ | GAA | P10253 | 7/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 8/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL379196 | 0.77 | MAPT (0.57) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL10335995 | 0.77 | MAPT (0.74) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL16977022 | 0.75 | MAPT (0.51) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL4184589 | 0.75 | MAPT (0.55) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL4184585 | 0.75 | MAPT (0.55) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL13596605 | 0.74 | NOX1 (0.58) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL28508988 | 0.74 | MAPT (0.57) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL15515688 | 0.74 | MAPT (0.53) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL28115197 | 0.74 | MAPT (0.53) | MAPTGAASMN1; SMN2RAB9ALMNA | |
| SCHEMBL28115196 | 0.74 | MAPT (0.53) | MAPTGAASMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753422-B1 | SMALL MOLECULE INHIBITORS FOR MRP1 AND OTHER MULTIDRUG TRANSPORTERS | CLEVELAND CLINIC FOUNDATION (US) | 2008-05-28 | — | — | EP | disclosed |