Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 9/20 | 0.48 |
| ▸ | GAA | P10253 | 7/20 | 0.48 |
| ▸ | MEN1 | O00255 | 5/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109406 | 0.79 | NOX1 (0.62) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL16111930 | 0.79 | NOX1 (0.62) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL16111932 | 0.79 | NOX1 (0.62) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3074599 | 0.75 | NOX1 (0.58) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL28226616 | 0.75 | NOX1 (0.58) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL1005100 | 0.75 | NOX1 (0.58) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL3074596 | 0.75 | NOX1 (0.58) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL30457035 | 0.75 | NOX1 (0.58) | NOX1MAPTGAAMEN1KMT2A | |
| SCHEMBL14199481 | 0.74 | MAPT (0.61) | MAPTGAAMEN1KMT2ARAB9A | |
| SCHEMBL7453557 | 0.73 | NOX1 (0.56) | NOX1MAPTGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318402-A1 | RUTHENIUM (II) COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURG (GB) | 2009-12-24 | — | — | US | disclosed |
| US-20090318402-A1 | RUTHENIUM (II) COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURG (GB) | 2009-12-24 | — | — | US | disclosed |
| WO-2007101997-A1 | RUTHENIUM (II) COMPOUNDS | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318402-A1 | RUTHENIUM (II) COMPOUNDS | NR0B1, NR0B2, NR2E1 | NOX1 74/4885MAPT 4241/4885GAA 4850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.