Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.69 |
| ▸ | HPGD | P15428 | 7/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.66 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.64 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | KDR | P35968 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PPARG | P37231 | 1/20 | 0.59 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801817 | 0.89 | KMT2A (0.67) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29270300 | 0.83 | KMT2A (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2803970 | 0.82 | KMT2A (0.59) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL6591353 | 0.81 | MAOB (0.70) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL15499731 | 0.79 | ALDH1A1 (0.81) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL29881770 | 0.79 | ALDH1A1 (0.80) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL2803955 | 0.79 | ALDH1A1 (0.80) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL11316690 | 0.79 | AR (0.74) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL3210418 | 0.78 | ALDH1A1 (0.79) | KMT2AMEN1ALDH1A1KDM4EHPGD | |
| SCHEMBL5717615 | 0.78 | AR (0.73) | KMT2AMEN1ALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108557-A1 | Modified Proteins | NOVO NORDISK HEALTHCARE A/G (CH) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108557-A1 | Modified Proteins | PTMS, DNPEP, STT3A | KMT2A 2057/4885MEN1 2695/4885ALDH1A1 3891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.