Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.81 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.81 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.81 |
| ▸ | AR | P10275 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | KDR | P35968 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4261716 | 0.90 | ALDH1A1 (1.00) | ALDH1A1KDM4EHSD17B10KMT2AMEN1 | |
| SCHEMBL20364004 | 0.88 | ALDH1A1 (0.77) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL29270309 | 0.87 | MAOA (0.65) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL29881770 | 0.86 | ALDH1A1 (0.80) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL11316690 | 0.86 | AR (0.74) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL2803955 | 0.86 | ALDH1A1 (0.80) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL5717615 | 0.85 | AR (0.73) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL3210418 | 0.85 | ALDH1A1 (0.79) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL14883408 | 0.83 | ALDH1A1 (0.79) | ALDH1A1KDM4EHSD17B10ARPOLB | |
| SCHEMBL6320632 | 0.83 | POLB (1.00) | ALDH1A1KDM4EHSD17B10ARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140066537-A1 | ORGANIC COMPOSITIONS FOR REPEATEDLY ADJUSTABLE OPTICAL ELEMENTS AND SUCH ELEMENTS | UNIVERSITE DE LIEGE (BE) | 2014-03-06 | — | — | US | disclosed |