Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8247006 | 0.89 | LOXL2 (0.47) | LMNAHTTSMN1; SMN2L3MBTL1BRD4 | |
| SCHEMBL30399922 | 0.84 | L3MBTL1 (0.49) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL15871964 | 0.84 | BRD4 (0.49) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL10163771 | 0.84 | L3MBTL1 (0.49) | SMN1; SMN2L3MBTL1BRD4NAMPTGRM2 | |
| SCHEMBL13391259 | 0.83 | L3MBTL1 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL30392761 | 0.83 | L3MBTL1 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL337888 | 0.83 | L3MBTL1 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL4896757 | 0.83 | BRD4 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL29715035 | 0.83 | BRD4 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A | |
| SCHEMBL14228526 | 0.83 | BRD4 (0.48) | L3MBTL1BRD4NAMPTGRM2KDM4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8778874-B2 | Glycopeptide antibiotic monomer derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | SHIONOGI & CO., LTD. (JP) | 2008-04-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080097078-A1 | Antibacterial activity against vancomycin-resistant bacteria | CSGALNACT1, MON2, NR2C2 | LMNA 4466/4885HTT 3061/4885SMN1; SMN2 3927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.