Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200211 | 0.91 | — | — | |
| SCHEMBL14518426 | 0.83 | CA1 (0.39) | CA1CA12CA2CA14 | |
| SCHEMBL14200225 | 0.83 | CA1 (0.39) | CA1CA12CA2CA14 | |
| SCHEMBL14200214 | 0.81 | CA1 (0.36) | CA1CA12CA2CA14 | |
| SCHEMBL14200184 | 0.79 | CA1 (0.48) | CA1CA12CA2CA14 | |
| SCHEMBL14200183 | 0.77 | CA1 (0.39) | CA1CA12CA2CA14 | |
| SCHEMBL14200207 | 0.76 | CA1 (0.38) | CA1CA12CA2CA14 | |
| SCHEMBL14200208 | 0.74 | CA1 (0.43) | CA1CA12CA2CA14 | |
| SCHEMBL14201304 | 0.74 | CA1 (0.36) | CA1CA12CA2CA14 | |
| SCHEMBL14200221 | 0.74 | CES1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |