SCHEMBL14200326

SCHEMBL14200326

COC(=O)c1cc(C(C)C)cc(C(C)C)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 4/20 0.54
CA2 P00918 4/20 0.54
CA12 O43570 3/20 0.54
CA7 P43166 3/20 0.54
CA9 Q16790 3/20 0.54
CA14 Q9ULX7 3/20 0.54
KDM4E B2RXH2 5/20 0.52
XDH P47989 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
LMNA P02545 2/20 0.52
GAA P10253 2/20 0.52
POLB P06746 1/20 0.52
NFKB1 P19838 1/20 0.52
GFER P55789 1/20 0.52
NFKB2 Q00653 1/20 0.52
RELA Q04206 1/20 0.52
FUT7 Q11130 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
ALDH1A1 P00352 3/20 0.48
MAPT P10636 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14682706 0.96 CA1 (0.54) CA1CA2CA12CA7CA9
SCHEMBL1188951 0.88 CA12 (0.68) CA1CA2CA12CA7CA9
SCHEMBL12180750 0.88 SLC7A5 (0.49) CA1CA2CA12CA7CA9
SCHEMBL21032129 0.87 ALDH1A1 (0.47) CA1CA2CA12CA7CA9
SCHEMBL21839916 0.87 CA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL16956840 0.87 CA1 (0.46) CA1CA2CA12CA7CA9
SCHEMBL16950320 0.84 SLC7A5 (0.46) CA1CA2CA12CA7CA9
SCHEMBL7695307 0.84 KDM4E (0.55) CA1CA2CA12CA7CA9
SCHEMBL20043786 0.84 HSD17B10 (0.49) CA1CA2CA12CA7CA9
SCHEMBL16950319 0.84 CA12 (0.43) CA1CA2CA12CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11767281-B2 Manufacturing and purification technology for high purity Propofol Chodankar Nandkumar Kashinath (IN) 2023-09-26 US disclosed
US-20230159420-A1 MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL Chodankar Nandkumar Kashinath (IN) 2023-05-25 US disclosed
EP-4100384-A1 SIMPLE MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL Chodankar, Nandkumar (IN) 2022-12-14 EP disclosed
WO-2021156776-A1 SIMPLE MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL CHODANKAR NANDKUMAR (IN) 2021-08-12 WO disclosed
US-8778874-B2 Glycopeptide antibiotic monomer derivatives NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2014-07-15 US disclosed
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria SHIONOGI & CO., LTD. (JP) 2008-04-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230159420-A1 MANUFACTURING AND PURIFICATION TECHNOLOGY FOR HIGH PURITY PROPOFOL MGMT, SUZ12, U2AF1 CA1 1644/4885CA2 935/4885CA12 1471/4885
US-11767281-B2 Manufacturing and purification technology for high purity Propofol MGMT, SUZ12, U2AF1 CA1 1644/4885CA2 935/4885CA12 1471/4885
US-20080097078-A1 Antibacterial activity against vancomycin-resistant bacteria CSGALNACT1, MON2, NR2C2 CA1 3378/4885CA2 2487/4885CA12 2022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.