Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLYCD | O95822 | 4/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14200620 | 0.95 | MLYCD (0.34) | MLYCDNPC1HPGDRAB9A | |
| SCHEMBL14200634 | 0.93 | MLYCD (0.35) | MLYCD | |
| SCHEMBL14200619 | 0.93 | PDK1 (0.32) | PDK1 | |
| SCHEMBL14200621 | 0.90 | NPC1 (0.33) | NPC1HPGDRAB9A | |
| SCHEMBL14228877 | 0.86 | MLYCD (0.43) | MLYCDPDK1NPC1 | |
| SCHEMBL14200618 | 0.85 | — | — | |
| SCHEMBL14229040 | 0.81 | MLYCD (0.43) | MLYCDNPC1 | |
| SCHEMBL14228946 | 0.78 | MLYCD (0.44) | MLYCDNPC1RAB9A | |
| SCHEMBL14229161 | 0.78 | TP53 (0.38) | MLYCDPDK1 | |
| SCHEMBL14200639 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |