Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14201012 | 0.91 | PSEN1 (0.32) | L3MBTL1 | |
| SCHEMBL14201009 | 0.89 | L3MBTL1 (0.33) | L3MBTL1MEN1LMNAKMT2APOLB | |
| SCHEMBL14201020 | 0.88 | MLYCD (0.30) | L3MBTL1 | |
| SCHEMBL14229413 | 0.85 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL14200856 | 0.84 | L3MBTL1 (0.32) | L3MBTL1MEN1LMNAKMT2A | |
| SCHEMBL14201106 | 0.82 | L3MBTL1 (0.31) | L3MBTL1 | |
| SCHEMBL14200889 | 0.78 | HDAC8 (0.33) | — | |
| SCHEMBL14200977 | 0.78 | AKR1B1 (0.34) | MEN1KMT2A | |
| SCHEMBL14200854 | 0.78 | L3MBTL1 (0.34) | L3MBTL1POLBAPEX1 | |
| SCHEMBL14229076 | 0.77 | PSEN1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7365093-B2 | Endothelin antagonists | ABBOTT LABORATORIES (US) | 2008-04-29 | — | — | US | disclosed |
| US-7208517-B1 | Endothelin antagonists | ABBOTT LABORTORIES (US) | 2007-04-24 | — | — | US | disclosed |