Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14539950 | 1.00 | TRPM8 (0.47) | TRPM8KDM4ERELAKCNA3ALDH1A1 | |
| SCHEMBL14159377 | 1.00 | TRPM8 (0.47) | TRPM8KDM4ERELAKCNA3ALDH1A1 | |
| SCHEMBL14541431 | 0.91 | TRPM8 (0.54) | TRPM8KDM4ERELAKCNA3ALDH1A1 | |
| SCHEMBL25987505 | 0.88 | KCNA3 (0.43) | TRPM8KDM4EKCNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL14541113 | 0.86 | RELA (0.38) | TRPM8RELAALDH1A1SMN1; SMN2APP | |
| SCHEMBL14199995 | 0.86 | RELA (0.38) | TRPM8RELAALDH1A1SMN1; SMN2APP | |
| SCHEMBL14817427 | 0.84 | KCNA3 (0.48) | TRPM8KDM4EKCNA3ALDH1A1SMN1; SMN2 | |
| SCHEMBL12128481 | 0.81 | TRPM8 (0.39) | TRPM8KDM4ERELAAPPMEN1 | |
| SCHEMBL10128968 | 0.81 | RELA (0.57) | TRPM8KDM4ERELAALDH1A1APP | |
| SCHEMBL17430457 | 0.81 | RELA (0.57) | TRPM8KDM4ERELAALDH1A1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1926159-A1 | ASYMMETRIC FLUORENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT CONTAINING THE SAME | IDEMITSU KOSAN COMPANY LIMITED (JP) | 2008-05-28 | — | — | EP | disclosed |