Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8161084 | 0.91 | GSTP1 (0.57) | MAOBGSTP1LMNACYP1A2PTGS1 | |
| SCHEMBL6417992 | 0.82 | CA4 (0.44) | LMNACYP1A2MEN1KMT2ARAB9A | |
| SCHEMBL8591645 | 0.79 | CA1 (0.48) | MAOBPTGS2KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL791985 | 0.79 | MAOB (0.69) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL6201495 | 0.78 | MAOB (0.51) | MAOBLMNACYP1A2PTGS1SLC6A2 | |
| SCHEMBL27574044 | 0.78 | LMNA (0.53) | MAOBGSTP1LMNACYP1A2PTGS1 | |
| SCHEMBL8161024 | 0.78 | GSTP1 (0.43) | MAOBGSTP1LMNACYP1A2PTGS1 | |
| SCHEMBL19091938 | 0.76 | GSTP1 (0.63) | MAOBGSTP1BCHEMEN1KMT2A | |
| SCHEMBL1420029 | 0.76 | ESR2 (0.59) | MEN1KMT2ARAB9ASMN1; SMN2GAA | |
| SCHEMBL20367158 | 0.76 | GSTP1 (0.63) | MAOBGSTP1BCHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297133-A1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | Envivo Pharmaceuticals, Inc. (US) | 2011-03-23 | — | — | EP | disclosed |
| WO-2009158393-A1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | ENVIVO PHARMACEUTICALS, INC. (US) | 2009-12-30 | — | — | WO | disclosed |