Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8591645 | 0.88 | CA1 (0.48) | NPC1RAB9AKDM4ETDP1BACE1 | |
| SCHEMBL1420156 | 0.82 | MAOB (0.50) | NPC1RAB9AALDH1A1LMNANPSR1 | |
| SCHEMBL28208024 | 0.81 | MEN1 (0.42) | NPC1RAB9AKDM4EALDH1A1LMNA | |
| SCHEMBL1420029 | 0.81 | ESR2 (0.59) | LTA4HNPC1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL28904555 | 0.81 | APP (0.41) | NPC1RAB9ASMN1; SMN2CA12CA1 | |
| SCHEMBL28961082 | 0.79 | LTA4H (0.48) | LTA4HNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL28150942 | 0.78 | ESR2 (0.48) | NPC1RAB9AKDM4ETDP1BACE1 | |
| SCHEMBL28433765 | 0.76 | METAP2 (0.36) | SMN1; SMN2MAPT | |
| SCHEMBL27860514 | 0.76 | APP (0.43) | CA4ALDH1A1L3MBTL1HTTSMN1; SMN2 | |
| SCHEMBL7123909 | 0.73 | HPGD (0.42) | NPC1RAB9AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | claimed |
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | claimed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | claimed |
| CN-116768796-A | Novel pyrazole-3-carboxamide derivative and preparation method and application thereof | 河北农业大学 | 2023-09-19 | — | — | CN | disclosed |
| CN-112390697-B | Synthesis method of N-arylselenium/thioethyl sulfoxide imine | 成都理工大学 | 2023-03-10 | — | — | CN | disclosed |
| CN-107353233-B | Method for catalytic synthesis of asymmetric azoxybenzene compound | 温州大学 | 2023-02-24 | — | — | CN | disclosed |
| CN-111087338-B | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2021-03-02 | — | — | CN | disclosed |
| CN-112390697-A | Synthesis method of N-arylselenium/thioethyl sulfoxide imine | 成都理工大学 | 2021-02-23 | — | — | CN | disclosed |
| CN-108424377-B | Method for synthesizing asymmetric azoxybenzene compound | 温州大学 | 2021-02-19 | — | — | CN | disclosed |
| CN-108689890-B | Method for synthesizing asymmetric azoxybenzene compound | 温州大学 | 2020-11-17 | — | — | CN | disclosed |
| CN-111087338-A | Sulfonamide-substituted pyrrolidones derivative and preparation method thereof | 常州大学 | 2020-05-01 | — | — | CN | disclosed |
| CN-108689890-A | A kind of synthetic method of asymmetric azobenzene oxide compound | 温州大学 | 2018-10-23 | — | — | CN | disclosed |
| CN-108424377-A | A kind of synthetic method of asymmetric oxidation azobenzene compound | 温州大学 | 2018-08-21 | — | — | CN | disclosed |
| CN-107353233-A | A kind of method for catalyzing and synthesizing asymmetric oxidation azobenzene compound | 温州大学 | 2017-11-17 | — | — | CN | disclosed |
| WO-2005092896-A1 | COMPOUND FOR INHIBITING TYROSINE KINASE ACTIVITY OF DDR2 PROTEIN | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2005-10-06 | — | — | WO | disclosed |