⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8561000 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL2386591 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL18239485 | 0.80 | LMNA (0.36) | — | |
| SCHEMBL18759639 | 0.74 | LMNA (0.41) | — | |
| SCHEMBL29347459 | 0.74 | LMNA (0.41) | — | |
| SCHEMBL5197168 | 0.74 | TSHR (0.41) | — | |
| SCHEMBL5824171 | 0.72 | — | — | |
| SCHEMBL25135489 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL11667581 | 0.71 | TSHR (0.39) | — | |
| SCHEMBL45342 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297229-A1 | POLYHYDROXYFUNCTIONAL POLYSILOXANE AS ANTI-ADHESIVE AND DIRT-REPELLANT ADDITIVES IN COATINGS POLYMERIC MOULDED MASSES AND THERMOPLASTICS METHOD FOR PRODUCTION AND USE THEREOF | Byk-Chemie GmbH (DE) | 2011-03-23 | — | — | EP | disclosed |
| WO-2010003610-A1 | POLYHYDROXYFUNCTIONAL POLYSILOXANE AS ANTI-ADHESIVE AND DIRT-REPELLANT ADDITIVES IN COATINGS POLYMERIC MOULDED MASSES AND THERMOPLASTICS METHOD FOR PRODUCTION AND USE THEREOF | BYK-CHEMIE GMBH (DE) | 2010-01-14 | — | — | WO | disclosed |