Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386591 | 1.00 | LMNA (0.36) | LMNAL3MBTL1TDP1TSHR | |
| SCHEMBL18239485 | 1.00 | LMNA (0.36) | LMNAL3MBTL1TDP1TSHR | |
| SCHEMBL18759639 | 0.83 | LMNA (0.41) | LMNA | |
| SCHEMBL29347459 | 0.83 | LMNA (0.41) | LMNA | |
| SCHEMBL5197168 | 0.83 | TSHR (0.41) | TSHR | |
| SCHEMBL5824171 | 0.81 | — | — | |
| SCHEMBL11667581 | 0.80 | TSHR (0.39) | TSHR | |
| SCHEMBL2892355 | 0.80 | LMNA (0.59) | LMNATSHR | |
| SCHEMBL1420306 | 0.80 | — | — | |
| SCHEMBL45342 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238648-B2 | Asymmetric synthesis method, related raw material and preparation method of (S,S)-2,8-diazabicyclo[4,3,0]nonane | SHANGHAI PUYI CHEMICAL TECHNOLOGY CO LTD (CN) | 2016-01-19 | — | — | US | disclosed |
| US-9238648-B2 | Asymmetric synthesis method, related raw material and preparation method of (S,S)-2,8-diazabicyclo[4,3,0]nonane | SHANGHAI PUYI CHEMICAL TECHNOLOGY CO LTD (CN) | 2016-01-19 | — | — | US | disclosed |
| US-20140066626-A1 | ASYMMETRIC SYNTHESIS METHOD, RELATED RAW MATERIAL AND PREPARATION METHOD OF (S,S)-2,8-DIAZABICYCLO[4,3,0]NONANE | Shanghai Puyi Chemical Technology Co. Ltd (CN) | 2014-03-06 | — | — | US | disclosed |
| US-20140066626-A1 | ASYMMETRIC SYNTHESIS METHOD, RELATED RAW MATERIAL AND PREPARATION METHOD OF (S,S)-2,8-DIAZABICYCLO[4,3,0]NONANE | Shanghai Puyi Chemical Technology Co. Ltd (CN) | 2014-03-06 | — | — | US | disclosed |
| US-5837868-A | REACTION OF DIHYDROXY OLEFINS IN A MULTISTAGE PROCESS ARYL METHYLAMINE TO FORM PYRROLIDINE INTERMEDIATE | ABBOTT LABORATORIES (US) | 1998-11-17 | — | — | US | disclosed |
| US-5703244-A | CYCLIZATION OF DIHYDROXY OLEFINS WITH TARTRATE ESTER IN PRESENCE OF TITANIUM ISOPROPOXIDE AND TERT-BUTYL HYDROPEROXIDE | ABBOTT LABORATORIES (US) | 1997-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066626-A1 | ASYMMETRIC SYNTHESIS METHOD, RELATED RAW MATERIAL AND PREPARATION METHOD OF (S,S)-2,8-DIAZABICYCLO[4,3,0]NONANE | SULT1E1, SULT1A1, PYM1 | LMNA 3407/4885L3MBTL1 2013/4885TDP1 2660/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.