SCHEMBL1420355

SCHEMBL1420355

O=C(O)c1cnno1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7556823 0.98
Formaldehyde SCHEMBL28743093 0.95 HCAR2 (0.38)
SCHEMBL8239364 0.78
SCHEMBL27578071 0.77 HCAR3 (0.32)
SCHEMBL25171101 0.72 NAPRT (0.41)
SCHEMBL4541454 0.64 PTGS2 (0.34)
SCHEMBL3642541 0.61
SCHEMBL2806245 0.60 HCAR2 (0.61)
SCHEMBL438341 0.60
SCHEMBL21998625 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102224596-A Improved cnt/topcoat processes for making a transplant conductor SAMSUNG ELECTRONICS CO LTD 2011-10-19 CN claimed
CN-101971345-A Nanostructured thin film LCD device UNIDYM INC 2011-02-09 CN claimed
CN-101522618-A 3-aza-bicyclo[3.1.0]hexane derivatives ACTELION PHARMACEUTICALS LTD (CH) 2009-09-02 CN claimed
CN-101475528-A Novel quinoline, tetrahydroquinazoline, and pyrimidine derivatives and methods of treatment related to the use thereof TAISHO PHARMACEUTICAL CO LTD (JP) 2009-07-08 CN claimed
CN-1798736-A Novel quinoline, tetrahydroquinazoline and pyrimidine derivatives and methods of treatment related to their use ARENA PHARM INC (JP) 2006-07-05 CN claimed
WO-2004087669-A1 NOVEL QUINOLINE, TETRAHYDROQUINAZOLINE, AND PYRIMIDINE DERIVATIVES AND METHODS OF TREATMENT RELATED TO THE USE THEREOF TAISHO PHARMACEUTICAL CO. LTD. (JP) 2004-10-14 WO claimed
CN-1358094-A Methods of treating chronic pain with MEK inhibitors WARNER LAMBERT CO (US) 2002-07-10 CN claimed
CN-1333754-A Benzoheterocycles and their use as MEK inhibitors WARNER LAMBERT CO (US) 2002-01-30 CN claimed
WO-2025068514-A1 SUBSTITUTED HETEROCYCLIC CARBOXAMINDES AND USE THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2025-04-03 WO disclosed
CN-113166079-A Redox active compounds and their use 克姆布鲁项目公司 2021-07-23 CN disclosed
CN-105646362-B 3- heteroaroylamino-propanoic derivatives and its purposes as drug 赛诺菲 2019-07-05 CN disclosed
CN-109641892-A 2- oxo-imidazol as reversible BTK inhibitor and pyridine and application thereof 默克专利有限公司 2019-04-16 CN disclosed
CN-109415346-A Novel pyrazole derivatives as ALK5 inhibitors and uses thereof 韩美药品株式会社 2019-03-01 CN disclosed
CN-107921138-A Therapeutic alliance including giving 2 amino, 3,5,5 trifluoro, 3,4,5,6 tetrahydropyridine H.隆德贝克有限公司 2018-04-17 CN disclosed
CN-1768047-A Benzo[1,2,5]oxadiazoles and benzo [1,2,5]thiadiazoles useful as histopathological staining agents, imaging agents and biomarkers. NOVARTIS AG (CH) 2006-05-03 CN disclosed
CN-1726201-A Substituted piperazines, (1,4) diaza * class and 2, 5-diazabicyclo (2.2.1) heptanes as histamine H1 and/or H3 antagonists or histamine H3 reverse antagonists GLAXO GROUP LTD (GB) 2006-01-25 CN disclosed
CN-1589271-A Fused heterocyclic succinimide compounds and analogs thereof as modulators of nuclear hormone receptor function BRISTOL MYERS SQUIBB CO (US) 2005-03-02 CN disclosed
CN-1177830-C Benzoheterocycles and their use as MEK inhibitors ��ʲ 2004-12-01 CN disclosed
CN-1358094-A Methods of treating chronic pain with MEK inhibitors WARNER LAMBERT CO (US) 2002-07-10 CN disclosed
CN-1333754-A Benzoheterocycles and their use as MEK inhibitors WARNER LAMBERT CO (US) 2002-01-30 CN disclosed