Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 14/20 | 0.65 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204743 | 0.91 | ADRB2 (0.77) | ADRB3ADRB2 | |
| SCHEMBL10658794 | 0.87 | ADRB3 (0.75) | ADRB3ADRB2 | |
| SCHEMBL5034400 | 0.85 | ADRB2 (0.89) | ADRB3ADRB2 | |
| SCHEMBL5034397 | 0.85 | ADRB2 (0.89) | ADRB3ADRB2 | |
| SCHEMBL14452358 | 0.83 | ADRB2 (0.80) | ADRB3ADRB2 | |
| SCHEMBL14451872 | 0.83 | ADRB2 (0.80) | ADRB3ADRB2 | |
| SCHEMBL5037637 | 0.83 | ADRB2 (0.89) | ADRB3ADRB2 | |
| SCHEMBL5037635 | 0.83 | ADRB2 (0.89) | ADRB3ADRB2 | |
| SCHEMBL14204727 | 0.82 | ADRB2 (0.46) | ADRB3ADRB2 | |
| SCHEMBL14204754 | 0.82 | ADRB2 (0.77) | ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7351742-B2 | Sulfonamide derivatives for the treatment of diseases | PFIZER INC. (US) | 2008-04-01 | — | — | US | disclosed |