Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.75 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14204770 | 0.87 | ADRB3 (0.65) | ADRB3ADRB2 | |
| SCHEMBL10665374 | 0.86 | ADRB2 (0.60) | ADRB3ADRB2 | |
| SCHEMBL10664103 | 0.85 | ADRB2 (0.69) | ADRB3ADRB2 | |
| SCHEMBL10656501 | 0.85 | ADRB2 (0.59) | ADRB3ADRB2 | |
| SCHEMBL10662739 | 0.84 | ADRB3 (0.54) | ADRB3ADRB2 | |
| SCHEMBL10657723 | 0.84 | ADRB3 (0.63) | ADRB3ADRB2 | |
| SCHEMBL10663303 | 0.83 | ADRB2 (0.58) | ADRB3ADRB2 | |
| SCHEMBL10659948 | 0.83 | ADRB2 (0.58) | ADRB3ADRB2 | |
| SCHEMBL9664001 | 0.81 | ADRB2 (0.63) | ADRB3ADRB2 | |
| SCHEMBL10662533 | 0.81 | ADRB2 (0.63) | ADRB3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4753962-A | HYPOGLYCEMIC, ANTIOBESITY AGENT | BEECHAM GROUP P.L.C. (GB) | 1988-06-28 | — | — | US | disclosed |
| US-4654371-A | ANTI-OBESITY, HYPOGLYCEMIA AGENTS | BEECHAM GROUP P.L.C. (GB) | 1987-03-31 | — | — | US | disclosed |
| US-4478849-A | HYPERGLYCEMIC AGENTS | BEECHAM GROUP LIMITED (GB) | 1984-10-23 | — | — | US | disclosed |
| EP-0006735-B1 | SECONDARY AMINES, THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE | BEECHAM GROUP PLC (GB) | 1983-06-15 | — | — | EP | disclosed |