Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ACP3 | P15309 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6028567 | 0.79 | CYP1A2 (0.51) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL25375484 | 0.76 | HDAC1 (0.55) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL28402183 | 0.75 | CYP1A2 (0.51) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL6685645 | 0.75 | LMNA (0.50) | KMT2AHTTCA2 | |
| SCHEMBL18942412 | 0.75 | TDP1 (0.62) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL66670 | 0.72 | TDP1 (0.69) | TDP1CYP1A2MTNR1AMEN1KMT2A | |
| SCHEMBL22651839 | 0.71 | CYP1A2 (0.59) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL4965935 | 0.71 | CYP1A2 (0.64) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL15224109 | 0.71 | CYP1A2 (0.54) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A | |
| SCHEMBL25376490 | 0.71 | CYP1A2 (0.50) | TDP1CYP1A2CYP2D6CYP2C19MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9526241-B2 | Dispersants for agricultural applications | AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) | 2016-12-27 | — | — | US | disclosed |
| US-9492543-B2 | Compositions for treating cognitive disorders | ALLERGAN, INC. (US) | 2016-11-15 | — | — | US | disclosed |
| EP-2296623-A1 | COMPOSITIONS FOR THE TREATMENT OF LICE | Sinclair Pharmaceuticals Limited (GB) | 2011-03-23 | — | — | EP | disclosed |
| CN-1248577-C | Pesticidal formulations | ICI PLC (GB) | 2006-04-05 | — | — | CN | disclosed |
| US-20050148709-A1 | Solid plant-protective formulations | CLARIANT GMBH (DE) | 2005-07-07 | — | — | US | disclosed |
| US-6767865-B2 | AGRICULTURE MIXTURES COMPRISING DISPERSANTS, WATER SOLUBLE COPOLYMERS, WETTING AGENTS, ADJUVANTS AND PLANT GROWTH REGULATORS, HERBICIDES OR PESTICIDES, USED AS SPRAYS ON PLANTS OR SOILS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 2004-07-27 | — | — | US | disclosed |
| US-20030161856-A1 | Agrochemical suspension formulations | CRODA INTERNATIONAL PLC (GB) | 2003-08-28 | — | — | US | disclosed |
| CN-1350426-A | Pesticidal formulations | ICI PLC (GB) | 2002-05-22 | — | — | CN | disclosed |