SCHEMBL4965935

SCHEMBL4965935

ON(Cc1cccc2ccccc12)Cc1cccc2ccccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.64
CYP2C19 P33261 3/20 0.64
CYP2D6 P10635 3/20 0.64
CYP2C9 P11712 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
ACP3 P15309 1/20 0.50
LMNA P02545 3/20 0.46
HTT P42858 3/20 0.46
NR1I2 O75469 2/20 0.46
SLC6A2 P23975 2/20 0.46
HTR2A P28223 2/20 0.46
SLC6A4 P31645 2/20 0.46
KCNH2 Q12809 2/20 0.46
SIGMAR1 Q99720 2/20 0.46
DRD2 P14416 1/20 0.46
ADRA2C P18825 1/20 0.46
CNR1 P21554 1/20 0.46
ADRA1A P35348 1/20 0.46
OPRK1 P41145 1/20 0.46
SLC6A3 Q01959 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7915221 0.82 CYP2D6 (0.69) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL17710475 0.79 CYP2C19 (0.60) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL820553 0.78 CYP2D6 (0.77) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL10932466 0.78 CYP2D6 (1.00) CYP1A2CYP2C19CYP2D6CYP2C9LMNA
SCHEMBL31316173 0.78 CYP2D6 (0.77) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
Hydrochloric Acid SCHEMBL146079 0.77 CYP2D6 (0.74) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
Hydrochloric Acid SCHEMBL2278072 0.77 CYP2D6 (0.74) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL2142323 0.77 CYP2D6 (0.74) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
SCHEMBL659516 0.77 CYP2C19 (0.60) CYP1A2CYP2C19CYP2D6CYP2C9TDP1
Naphthalen-1-Yl-Methanol SCHEMBL28403 0.77 CYP1A2 (0.60) CYP1A2CYP2C19CYP2D6CYP2C9TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP claimed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP claimed
US-20080315155-A1 Diamines Having Reduced Color ALBEMARLE CORPORATION (US) 2008-12-25 US disclosed
US-20080262187-A1 Blends of Diamines Having Reduced Color ALBEMARLE CORPORATION (US) 2008-10-23 US disclosed
EP-1966122-A1 DIAMINES HAVING REDUCED COLOR Albermarle Corporation (US) 2008-09-10 EP disclosed
EP-1966265-A2 BLENDS OF DIAMINES HAVING REDUCED COLOR Albermarle Corporation (US) 2008-09-10 EP disclosed
WO-2007079365-A2 BLENDS OF DIAMINES HAVING REDUCED COLOR ALBEMARLE CORPORATION (US) 2007-07-12 WO disclosed
WO-2007079367-A1 DIAMINES HAVING REDUCED COLOR ALBEMARLE CORPORATION (US) 2007-07-12 WO disclosed
EP-0941866-B1 Thermally imageable element having improved room light stability DU PONT (US) 2003-04-16 EP disclosed
US-6251571-B1 MIXTURE OF OXIDIZER, DYE AND HYDROXYLAMINE E. I. DU PONT DE NEMOURS AND COMPANY 2001-06-26 US disclosed
EP-0941866-A1 Non-photosensitive, thermally imageable element having improved room light stability E. I. du Pont de Nemours and Company (US) 1999-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080262187-A1 Blends of Diamines Having Reduced Color DDT, DDC, AOC1 CYP1A2 524/4885CYP2C19 1655/4885CYP2D6 627/4885
US-20080315155-A1 Diamines Having Reduced Color DDT, DPYD, DDC CYP1A2 821/4885CYP2C19 2477/4885CYP2D6 1003/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.