Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | FBP1 | P09467 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | NQO2 | P16083 | 3/20 | 0.41 |
| ▸ | P4HB | P07237 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6546605 | 0.85 | ESR1 (0.68) | ALDH1A1CYP2A6ESR1ESR2KMT2A | |
| SCHEMBL18790028 | 0.85 | ESR1 (0.68) | ALDH1A1CYP2A6ESR1ESR2KMT2A | |
| SCHEMBL8733151 | 0.80 | ESR1 (0.45) | ALDH1A1CYP2A6ESR1ESR2FBP1 | |
| SCHEMBL8733154 | 0.80 | ESR1 (0.45) | ALDH1A1CYP2A6ESR1ESR2FBP1 | |
| SCHEMBL9006748 | 0.76 | ESR1 (0.41) | ALDH1A1ESR1ESR2FBP1KMT2A | |
| SCHEMBL9006537 | 0.76 | ESR1 (0.41) | ALDH1A1ESR1ESR2FBP1KMT2A | |
| SCHEMBL9006528 | 0.76 | ESR1 (0.41) | ALDH1A1ESR1ESR2FBP1KMT2A | |
| SCHEMBL9006745 | 0.76 | ESR1 (0.41) | ALDH1A1ESR1ESR2FBP1KMT2A | |
| SCHEMBL6547576 | 0.76 | ESR1 (0.55) | ALDH1A1ESR1ESR2KMT2APTGS2 | |
| SCHEMBL4602278 | 0.76 | MAPT (0.59) | ALDH1A1ESR1ESR2KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7361288-B2 | Components for high-frequency technology | MERCK PATENT GESELLSCHAFT MIT BESSCHRANKTER HAFTUNG (DE) | 2008-04-22 | — | — | US | disclosed |